Lactobacillus sporogenes, the Main Ingredient in Candida-G/Flora-G Plus
Candida-G’s companion product, Flora-G Plus, contains Lactobacillus Sporogenes (1 Billion CFUs), FOS (fructose Oligo Saccharides) (150 mg), ginger (20 mg) and flaxseed (10 mg).
Lactobacillus sporogenes represents a breakthrough in Lactobacillus supplementation — a safe, stable, effective, L(+)-lactic-acid-producing organism. It was originally isolated and described in 1933. The organism requires a complex mixture of organic substrates for growth, including fermentable carbohydrates and peptides (fructoseoligosaccharides).
L. sporogenes is a universally occurring, gram-positive, spore forming, lactic acid producing and beneficial bacterium. L. sporogenes is a probiotic, which supports the growth of friendly bacteria and helps maintain a healthy balance of microflora in the intestinal environment.
Unlike other strains of lactobacillus, L. sporogenes does not require refrigeration to maintain its peak potency (as measured by live colony forming units, CFUs).
L. sporogenes is better adapted to survive gastric acidity due to its spores. The spore coat protects the bacteria from the low pH of the stomach, but also swells in contact with the gastric juices such that by the time the bacteria reaches the intestine, it has shed its spore and germinates in the intestine.
L. sporogenes supports levels of healthy microflora thereby improving the gastrointestinal ecology. It also produces only the L(+) form of lactic acid, which is completely metabolized in the body.
L. sporogenes is considered a semi-resident, indicating it takes up only a temporary residence in the human intestines, which emphasizes the importance of continued supplementation.
L. sporogenes is effective before, during and after antibiotic therapy.
Seventy percent of individuals suffering from chronic constipation treated with 300-750 million spores per day of L. sporogenes for two to 10 days experienced an amelioration of abdominal distention and a normalization of stools.
L. sporogenes binds cholesterol in the gut, and may inhibit the cholesterol-producing enzyme HMG CoA Reductase. (360 million spores/day decreased total serum cholesterol from an average of 330 mg/dL to 226 mg/dL in 17 subjects with type II hyperlipidemia over a three-month interval. HDL-cholesterol increased slightly. No changes in serum triglyceride levels were observed).
Adverse reactions in humans following supplementation with L. sporogenes have not been reported. A reasonable dose is three to four billion colony-forming units (CFU’s) two to three times daily.
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